In order that users can read E-books more intuitively and comfotablely, the E-paper Book emerged for E-books' wide applications in daily life. In this paper, design of graphical user interface of E-paper Book is implemented based on Linux operating system, with Qt graphical user interface development tools. Then, text documents can be showed on the electronic paper. The program implements the creation of the main window and some dialog boxes, and the switching and the interaction between the main window and the dialog boxes. Then, text documents decoding and paging of the different encoding methods are implemented in the process of loading text documents.