Modern combat System of Systems (SoS) generally consists of complex systems across various fields. Accordingly, multiple modeling and simulation tools are used for SoS development. As a result, several problems are caused. For example, heterogeneous data is hard to share among modeling tools, and the collaboration between modeling and simulation tools is difficult. To address these problems, we propose a new multi-architecture SoS modeling and simulation platform with the development capability including meta-model development, SoS modeling, as well as simulation and verification. Then, we demonstrate the platform through a man-aircraft cooperative defense scenario in the air-ground cooperative defense SoS. Specifically, the meta-models for the case scene are designed, and the operational view models are built via the proposed platform. In addition, the simulation of aircraft behavior in combat missions provides a theoretical basis for the trade-off of combat plans.