This paper introduced a new data collection system based on android platform,and achieved USB communication between Android and LPC2142. It describes the development process of the android USB application, and on the basis implements USB communication between Android system and AMR platform. It is the latest application development based on revenue of mobile terminal Android. The front-end uses LPC2142 A/D interface to collect data and sent it to back-end through USB data wire. The back-end use the USB interface which is based on Android 3.1 platform to receive data and show the wave on the Android Tablet PC. So this design has wide application prospect.