This article researches the problem of efficient energy saving in wireless sensor network routing. The nodes in wireless sensor network need primary energy such as battery to supply energy. But it is impossible to provide extra energy supplement in many adverse circumstances. The traditional route protocol of wireless sensor network mainly focuses on the quality of network or energy solving. Some nodes may die when the good quality network works too long. On the contrary, the quality of the network can not be guaranteed if the energy saving has been considered only. Thus this paper proposes a method of high usage route of wireless sensor network based on dynamic epistemic PSO. And a dynamic epistemic PSO algorithm is introduced in searching the route of sensor nodes after the analyzing of the structure of the wireless network, which can realize the real-time monitoring of the current energy state of nodes and the information of route and then achieve the effective balanced state of the routes. The simulation experiments show that through this method, the updated energy consumption of wireless network is reduced efficiently, the death date of nodes is also reduced and the performance of network is improved obviously.