The open management of experiment teaching can encourage college students to carry out personalized learning and autonomous learning, and will help students sharpen up their self-study skills and exploration competence. This paper designs and develops an open experiment teaching management system for universities based on ASP.NET, in which the open resource project FrameWork is used as infrastructure. The upper application functions are developed, such as experiment reservation management, experiment course management, laboratory management. The perfect algorithms about reservation time restraints test and dynamic generating of visual experiment table are designed. This system can meet complex requirements from open experiment management, and has high use value.