Based on the relating theories and technologies of the light barrier type naked-eye 3D technology, combining hardware platform of the current mainstream 2D digital photo frame as well as integrating optical barrier-style 3D LCD screen to digital photo frame products, this paper discusses software platform of digital photo frame based on the naked-eye 3D technology and probes its key algorithm. With the implementation of the digital photo frame based on the light barrier type naked-eye 3D technology and the relevant verification as well as the ultimate test results, it is approved that the design of digital photo frame based on the naked eye 3D technology can achieve the ideal designed features and performance. Therefore, it has certain value of application and popularization.