To solve the problem of the inefficient identification and the large amount of data transmission, an enhanced group-based anti-collision algorithm based on partial responses for RFID tag was proposed. The algorithm used the grouping strategy and partial response mode combines. The tags in each group were identified by reader in turn, it could reduce the probability of collision and the number of the identified tags. The partial response mechanism was used to identify all tags in each group, it reduce the data traffic effectively. The simulation results show that, compared with several other algorithms, the proposed algorithm has the advantage of efficient identification and a small amount of data exchange.