In this paper, we put forward the communication implementation of the upper computer with the software of Labview and lower computer PLC-300 based on OPC UA technology. The communication is data exchanging between two PC machines. One PC acts as a client, the other one acts as a server, and the server is connected to the PLC-300. The client connects to the server through UA, and then it can realize the communication between Labview and PLC on the client machine. This paper introduces how to create UA Client which can be safely connected with UA Server, and how to finally realize the secure communication between PLC and Labview. In Labview, the data can be displayed in real time when it changes in PLC, and the collected data can be save in the form of text files for follow-up observation and playback. The feasibility of this method is verified by experiments. The system has the advantages of short development period, strong flexibility and system stability. Finally, we fully validate the feasibility of using this method to data communications.