Because of low level of indoor medical information system, lack of remote monitoring, and insufficient medicine delivery research, the current system cannot meet the actual demand. In this study, we proposed an intelligent medicine delivery system framework based on cloud technology and Internet of Things (IoT); set up a new indoor medical and medicine robot delivery system based on embedded system, RFID, IEEE 802.11 communication protocol, and cloud technology. Then, we designed a remote mobile and PC terminal management system. Finally, we constructed the experimental and measured performances of the system and the mobile delivery robot. The experimental results show that the fastest control cycle of network nodes is 48 s per time, and the average period is 48.3 per time. The system delivers a medicine with an average time of 4.19 s. System upload cloud data, the fastest upload storage time is 2.1 s, the average cost is 5.21 s and the communication success rate is greater than 90%.