According to the actual needs of intelligent household, environmental monitoring etc, this paper designed a wireless sensor node of long-distance communication system. This system used the second SoC CC2530 set in RF and controller chips as the core module and externally connected with CC2591 RF front-end power amplifier module. Based on ZigBee2006 in software agreement stack, it realized each application layer function based on ZStack. It also introduced wireless data acquisition networks based on the ZigBee agreement construction, and has given the hardware design schematic diagram and the software flow chart of sensor node, synchronizer node. The experiment proved that the node is good in performance and the communication is reliable. The communication distance has increased obviously compared with the first generation TI product.