According to present status of information construction in paper-making enterprise, information integration technologies are performed to build multifunctional integration system in order to effectively solve a series of problems which paper industry faces. The suitable functional framework architecture for paper-making enterprise is researched as well as key integrated technologies such as information modeling, system interface design and OPC-based data collection are described on the basis of deep investigation. Finally, a paper-making enterprise in Fuyang, Zhejiang Province is as an example, which the interactive control network topology structure and some key system implementations are introduced. At present, the system has been successfully put in application.